The role of plasmapheresis in the treatment of severe lupus nephritis : a case report
Joint Authors
Husayn, Majdi
Mooij, Jacob
al-Sayyid, Hassan
Roujouleh, Haytham M.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 6, Issue 4 (31 Aug. 1995), pp.412-416, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
1995-08-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
There is still controversy about the efficacy of plasma exchange in the treatment of severe lupus nephritis.
Some studies have reported no beneficial effect with plasma exchange, while others claim its usefulness when used in combination ("synchronization") with immunosuppressive drugs, particularly intravenous (i.v.) pulse doses of cyclophosphamide.
We report here a 13 year old girl who presented twice with severe exacerbation of lupus nephritis (WHO class IV) leading to acute renal failure (ARF) necessitating dialysis, and who on both occasions responded well to i.v.
pulse doses of cyclophosphamide and methylprednisolone plus plasma exchange.
The second episode of ARF had occurred in spite of the patient being on maintenance therapy with prednisolone and i.v.
cyclophosphamide.
The course in this patient supports the view that the addition of plasma exchange to i.v.
pulse cyclophosphamide might be effective in patients with severe lupus nephritis unresponsive to immunosuppressive drugs alone.
American Psychological Association (APA)
Husayn, Majdi& Mooij, Jacob& Roujouleh, Haytham M.& al-Sayyid, Hassan. 1995. The role of plasmapheresis in the treatment of severe lupus nephritis : a case report. Saudi Journal of Kidney Diseases and Transplantation،Vol. 6, no. 4, pp.412-416.
https://search.emarefa.net/detail/BIM-212620
Modern Language Association (MLA)
Husayn, Majdi…[et al.]. The role of plasmapheresis in the treatment of severe lupus nephritis : a case report. Saudi Journal of Kidney Diseases and Transplantation Vol. 6, no. 4 (December 1995), pp.412-416.
https://search.emarefa.net/detail/BIM-212620
American Medical Association (AMA)
Husayn, Majdi& Mooij, Jacob& Roujouleh, Haytham M.& al-Sayyid, Hassan. The role of plasmapheresis in the treatment of severe lupus nephritis : a case report. Saudi Journal of Kidney Diseases and Transplantation. 1995. Vol. 6, no. 4, pp.412-416.
https://search.emarefa.net/detail/BIM-212620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 416
Record ID
BIM-212620