The impact of non-HLA factors on renal graft survival
Joint Authors
Hassan, Ahmad Adil
Amin, Isam Muhammad
Amin, Ahmad Ibrahim
Amin, Ahmad Ibrahim
Umar, Isam Lutfi
Ali, Muhammad Hassan
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 5, Issue 3 (30 Jun. 1994), pp.359-364, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
1994-06-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Several non-HLA factors such as, age, sex, blood group, and cytomegalovirus (CMV) carrier state of both the donor and the recipient are known to influence renal allograft survival.
In a retrospective study on 150 living related donor renal transplant patients, we evaluated the effect of the above mentioned factors on graft survival.
Patients were divided into two groups, according to immunosuppression protocols.
Group 1 (n=120) patients were on triple therapy with cyclosporin-A, azathioprine and prednisolone whereas those in Group 2 (n=30) were on conventional therapy with azathioprine and prednisolone.
In Group 1, the patients aged < 45 years had graft survival rates 100%, 94% and 83% at 1,2 and 3 years, whereas the rates were 87%, 87%, 68% respectively in those aged > 45 years (P < 0.06).
Sex of neither the donors nor the recipients affected graft survival.
Patients with blood group B had poor graft survival among Group 2 patients (P < 0.05).
However, the patients with blood group B in Group 1 had significantly superior graft survival rates than the patients with the same blood group in Group 2 (P < 0.01).
No significant difference in the graft survival rates was found between the two groups in relation to other blood groups.
Also, there was no significant difference in the graft survival of the CMV negative and the CMV positive (IgG) recipients in both the study groups.
American Psychological Association (APA)
Hassan, Ahmad Adil& Amin, Isam Muhammad& Amin, Ahmad Ibrahim& Umar, Isam Lutfi& Ali, Muhammad Hassan& Amin, Ahmad Ibrahim. 1994. The impact of non-HLA factors on renal graft survival. Saudi Journal of Kidney Diseases and Transplantation،Vol. 5, no. 3, pp.359-364.
https://search.emarefa.net/detail/BIM-214720
Modern Language Association (MLA)
Hassan, Ahmad Adil…[et al.]. The impact of non-HLA factors on renal graft survival. Saudi Journal of Kidney Diseases and Transplantation Vol. 5, no. 3 (December 1994), pp.359-364.
https://search.emarefa.net/detail/BIM-214720
American Medical Association (AMA)
Hassan, Ahmad Adil& Amin, Isam Muhammad& Amin, Ahmad Ibrahim& Umar, Isam Lutfi& Ali, Muhammad Hassan& Amin, Ahmad Ibrahim. The impact of non-HLA factors on renal graft survival. Saudi Journal of Kidney Diseases and Transplantation. 1994. Vol. 5, no. 3, pp.359-364.
https://search.emarefa.net/detail/BIM-214720
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 364
Record ID
BIM-214720