The risk factors for diabetes mellitus after kidney transplantation
Joint Authors
Heydarian, Peimaneh
Amerian, Monireh
Raziqi, Afat
Pourmand, Gholamreza
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 6 (31 Dec. 2010), pp.1038-1043, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-12-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Post-transplant diabetes mellitus (PTDM) is an adverse complication of kidney transplantation, associated with decreased graft and patient survival.
We investigated the risk factors for PTDM and their relation to graft rejection in our kidney transplant recipients.
We prospectively included 109 consecutive first kidney transplant recipients transplanted at the Sina Hospital in Tehran from June 2003 to May 2004.
Patients were excluded if they had diabetes at the time of transplantation either as the cause of kidney failure or as a comorbidity.
PTDM was defined by fasting blood sugar ?126 mg/dL or random blood sugar ?200 mg/dL on two occasions and the need for insulin therapy and/or oral hypoglycemic drugs for at least two weeks.
Thirty non-diabetic transplant recipients were diagnosed as having PTDM during the six month followup period after transplantation.
Sixty non-PTDM controls, matched for age, sex and immunosuppressive regimen, and transplanted as closely as possible to the PTDM cases, were randomly selected.
The risk factors for PTDM were investigated in these 90 transplant recipients.
Age older than 50 years (P = 0.04), history of hypertension (P = 0.02), polycystic kidney disease (P = 0.015), duration on dialysis more than one year (P < 0.0001), family history of diabetes mellitus (P < 0.0001), mean daily dose of prednisolone ?15 mg/day (P < 0.0001) and cyclosporine ?240 mg/day (P < 0.0001) were all more in the PTDM group.
Also, the mean serum triglycerides was higher (P = 0.019) and there was an increased risk of graft rejection (P < 0.0001) in the PTDM group.
American Psychological Association (APA)
Raziqi, Afat& Heydarian, Peimaneh& Amerian, Monireh& Pourmand, Gholamreza. 2010. The risk factors for diabetes mellitus after kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 6, pp.1038-1043.
https://search.emarefa.net/detail/BIM-215665
Modern Language Association (MLA)
Raziqi, Afat…[et al.]. The risk factors for diabetes mellitus after kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 6 (Dec. 2010), pp.1038-1043.
https://search.emarefa.net/detail/BIM-215665
American Medical Association (AMA)
Raziqi, Afat& Heydarian, Peimaneh& Amerian, Monireh& Pourmand, Gholamreza. The risk factors for diabetes mellitus after kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 6, pp.1038-1043.
https://search.emarefa.net/detail/BIM-215665
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1042-1043
Record ID
BIM-215665