Endoscopic fndings in uraemic patients with dyspeptic symptoms

Abstract EN

bjective : 1-To correlate the endoscopic findings with clinical diagnosis of patients with chronic renal failure in regard to the cause of their dyspeptic symptoms.

2-to find out the frequency of various mucosal lesions of upper gastrointestinal tract in these patients as shown by endoscopic examination in compares to the findings in non renal failure dyspeptic patients.

Patients and methods : A prospective study carried out between March 2007 to September 2007 on the admitted 25 uremic patients with dyspeptic symptoms in AL-Sader teaching hospital and AL-Hakeem general hospital in AL-NAJAF city in IRAQ.

(19 peritoneal dialysis and 6 patients on conservative treatment).

History and clinical examination had done for each patients and clinical diagnosis of the dyspeptic symptoms was made before the endoscopic examination.

Blood urea was measured in all patients and the patients are classified arbitrary in to four groups according to the level of the blood urea before endoscopic examination.

Also the endoscopic results of 1000 dyspeptic non uremic patients examined during the same period were also analyzed and compared with those of uremic patients.

Results : Clinical diagnosis depending on history and clinical examination was as follows.

4 patients highly suggestive of esophagit is, 9 patients highly suggestive of gastritis, 12 patients highly suggestive of peptic ulceration.

While the endoscopic results of the of the dyspeptic uremic patients were 15 patients got dudenitis, 12 patients got gastritis, 7 patients got esophagi is, 3 patients got esophageal hiatus hernia, 3 patients with normal finding.

Regarding the endoscopic the endoscopic findings of 1000 cases of non uremic patients with dyspeptic symptoms were esophagi is in 115 of the cases, gastritis in 113 of the cases, gastric ulcer in 35 of the cases, dudenitis in 190 of the cases, duodenal ulcer in 313 of the cases, other normal findings and others in 277 of the cases.

Conclusion : This study is clearly shown no peptic ulcer was detected in uremic patients involved in our study, while there is increase in the frequency of mucosal lesions in the form of esophagit is, gastritis, and dudenitis in compares with non uremic patients with dyspeptic symptoms.