Patterns of anti-hypertensive therapy in diabetic patients with and without reduced renal function
Joint Authors
Suwaylih, Walid M.
Sawalihah, Ansam F.
al-Jabi, Samah W.
Tamim, Iman J.
Zayyud, Said H.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 4 (30 Aug. 2010), pp.652-659, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-08-30
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
- Patients
- Endocrine glands
- Kidneys
- Diseases
- Penal functions
- Medical examinations
- Therapeutics
- Diabetes
- Hypertension
- Diabetics
Abstract EN
Renal function deterioration is a common complication in patients with diabetes mellitus and hypertension.
Appropriate use of anti-hypertensive agents and tight control of Blood Pressure (BP) can minimize and delay such complications.
This study was performed in order to investigate the utilization patterns of anti-hypertensive agents and to evaluate BP control among diabetic-hypertensive patients with and without reduced renal function.
In a retrospective cohort study, all diabetichypertensive patients attending The Al-Watani Medical Governmental Center from August 01, 2006 until August 01, 2007 were enrolled in the study.
Patients with congestive heart failure and/or endstage renal disease were excluded from the study.
The proportion of use of five different antihypertensive drug classes were compared for all patients receiving 1, 2, 3, or 4 drugs, and separately among patients with and without reduced renal function.
Over 60% of patients were receiving angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blocker (ARB), followed by diuretics (40.8%), calcium channel blockers (25.1%) and (?-blockers (12.5%).
The majority of patients (> 55%) were either on mono or no drug therapy.
Patients on monotherapy were mostly receiving ACEI/ARB (60%).
In patients with reduced renal function, use of diuretics, but not ACEI/ARB or CCB, was higher and 41.8% of the patients were on monotherapy compared to 46.6% in patients with normal renal function.
The proportion of patients achieving good BP control was 20% with monotherapy and 28% with combination therapy.
Our study suggests that the pattern of anti-hypertensive therapy was generally consistent with inter-national guidelines.
Areas of improvement include increasing use of ACEI/ARB and diuretics, decreasing the number of untreated patients, and increasing the proportion of patients with well controlled BP in this population.
American Psychological Association (APA)
Suwaylih, Walid M.& Sawalihah, Ansam F.& al-Jabi, Samah W.& Zayyud, Said H.& Tamim, Iman J.. 2010. Patterns of anti-hypertensive therapy in diabetic patients with and without reduced renal function. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 4, pp.652-659.
https://search.emarefa.net/detail/BIM-218400
Modern Language Association (MLA)
Suwaylih, Walid M.…[et al.]. Patterns of anti-hypertensive therapy in diabetic patients with and without reduced renal function. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 4 (Sep. 2010), pp.652-659.
https://search.emarefa.net/detail/BIM-218400
American Medical Association (AMA)
Suwaylih, Walid M.& Sawalihah, Ansam F.& al-Jabi, Samah W.& Zayyud, Said H.& Tamim, Iman J.. Patterns of anti-hypertensive therapy in diabetic patients with and without reduced renal function. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 4, pp.652-659.
https://search.emarefa.net/detail/BIM-218400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 658-659
Record ID
BIM-218400