Synthesis and microbial studies of 2-[(3'-trifluoromethylphenyl)‎amino]-3-[n4-{n1- (substituted benzothiazolyl)‎sulfanilamido}carbonyl]pyridines

Abstract EN

2-[(3'-Trifluoromethylphenyl)amino]-3-[N4 -{N1 -(substitutedbenzothiazolyl)sulfanilamido}carbonyl]- pyridine 7a-m containing different functional groups have been synthesized by the condensation of 2- amino substituted benzothiazoles 1a-m and p-acetamidobenzenesulfonyl chloride 2 in pyridine and acetic anhydride mixture.

The title compounds and their derivatives have been characterized by analytical and spectral studies (IR and 1H-NMR).

All the compounds have been screened for their antibacterial and antifungal activity.

Some of them found pronounced antibacterial activity.