Dipolar cycloaddition reactions in organic synthesis : synthesis of some new n-arylphthalimides and fully substituted pyrrolo [3,4 -h] quinolin derivatives

Abstract EN

N-Arylphthalimides 3a-e were prepared through the reaction of 2-amino-3-cyano-4- ethoxycarbonyl-5-methylfuran 1 and N-Arylmaleimides 2a-e.

Compounds 3a-e reacted with malononitrile, cyanoacetophenone, cyanothioacetamide and ethylcyanoacetate to give the corresponding pyrrolo [3,4-h] quinoline derivatives 4a-e, 5a-e, 6a-e and 7a-e respectively.

The structure of the newly synthesized compounds was established on the basis of elemental analysis and spectral data studies.