Synthesis of schiff bases derived from benzaldehyde and salicylaldehyde with some amino acids by a new develop method

Abstract EN

The project is aimed at the synthesis of some Schiff bases derived from benzaldehyde and salicylaldehyde with some amino acids as glycine, DL-alanine ßalanine, and L-methionine, with a new alternative method.

The development includes the use of 10-2mole sodium hydroxide as a new catalyst, which is added to the classical method of Schiff bases synthesis.

This method is applied successfuly to the synthesis of six imines from compounds mentioned.

The structures of these Schiff bases are confirmed by using physical methods, namely, melting points or boiling point, UV and IR spectra.

Finally a new suggested mechanism for the reaction mechanism is given, which is composed from three steps, on of them is slow, the other two are fast.