Relationship between lipid profile and renal function parameters in patients with acute myocardial infarction

Abstract EN

Background: Cardiovascular disease (CVD) is related to multiple metabolic risk factor as hypertension, diabetes mellitus, hyperlipidaemia and cystiene level, as well. Objective: To investigate the association between lipid pro file as risk index for CVD and renal function parameters in patients with acute myocardial infarction (AMI). Methods: One hundred and one patients (51 males, 50 females) with AMI admitted to Merjan Teaching Hospital in Hilla city on 2007 and fifty five (30 males, 25 females) apparently healthy persons as a controls subject to present study.

Determination of blood Total cholesterol (TC), triacylglycerol (TG), high density lipoprotein (HDL) cholesterol, serum creatinine (Cr) and serum uric acid (UA) were performed using colorimetric methods.

Very low density lipoprotein (VLDL)-cholesterol and low density lipoprotein (LDL) -cholesterol was determined using mathematical method.

Risk index of lipid profile determined by dividing TC / LDL –cholesterol. Results: Serum Cr and UA found to be significantly increased in patients with AMI when compared with healthy controls.

Total cholesterol, VLDL- cholesterol, LDLcholesterol and TG of patient with AMI in both gander found to be significantly increase when compared with healthy controls.

HDL-cholesterol of patients found to be decreased. Conclusion: Serum Cr and serum UA can be regarded as risk factor for patient with CVD.