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Synthesis and microbiological testing of some new derivatives of compounds containing active methylene group
Joint Authors
Musa, Amin
al-Helby, A. A.
al-Sawwah, M. M.
Bayyumi, A. H.
al-Azab, Adil S.
Sherbiny, F. F.
Source
Journal of Saudi Chemical Society
Issue
Vol. 10, Issue 1 (30 May. 2006), pp.77-93, 17 p.
Publisher
Publication Date
2006-05-30
Country of Publication
Saudi Arabia
No. of Pages
17
Main Subjects
Abstract AR
في هذا البحث أمكن تشييد سلسلة من مشتقات الكينولين و بريميدو الكينولين وتراى أزيبين -3- أون و تراى أزيين -3- ثيون.
و تم التأكيد البنائي لهذه المركبات الجديدة بواسطة التحاليل الدقيقة و الأشعة تحت الحمراء و الرنين المغناطيسي و كذلك مطياف الكتلة و بإجراء المسح البيولوجي على هذه المركبات, أظهرت النتائج فعالية بعض هذه المركبات كمضادات للبكتيريا و الفطريات مما يوضح أمكانية منها في المجال التطبيقي
Abstract EN
2-Amino-4-(substituted phenyl)-7, 7-dimethyl- (substituted phenyl)-4, 6, 7, 8-tetrahydro 1-quinoline-3-carboxylic acid amide, 2-Amino-1- (substituted phenyl)-7,7-dimethyl (substituted phenyl)-4 ,6, 7, 8 tetrahydro–1H-quinoline-3-carbonitrile-5-one, 5,10-Di [ (substituted phenyl)-8,8-dimethyl-5, 8, 9, 10-tetrahydro- 3 H, 7H-pyrimido (4, 5-b)] quinoline-4, 6-dione, 4- (substituted phenyl)-3, 4, 5, 6, 7, 8-hexahydro-1Hquinoline- 2-thione, 5-(substituted phenyl)-1, 2, 4, 5, 6, 7, 8, 9-octahydro benzo [f] [1, 2, 4] triazepine-4-one and 5 -(substituted phenyl)-1, 2, 4, 5, 6 ,7, 8, 9-octahydro-1H-benzo [f] [1, 2, 4] triazepine-3-thione were synthesized.
The microbiological testing of some of synthesized compounds showed that, some of the tested compounds having antibacterial and antifungal activity using cephalexine and nystaine as standard antibacterial and antifungal agents respectively.
American Psychological Association (APA)
al-Helby, A. A.& Musa, Amin& al-Sawwah, M. M.& Bayyumi, A. H.& al-Azab, Adil S.& Sherbiny, F. F.. 2006. Synthesis and microbiological testing of some new derivatives of compounds containing active methylene group. Journal of Saudi Chemical Society،Vol. 10, no. 1, pp.77-93.
https://search.emarefa.net/detail/BIM-24160
Modern Language Association (MLA)
al-Helby, A. A.…[et al.]. Synthesis and microbiological testing of some new derivatives of compounds containing active methylene group. Journal of Saudi Chemical Society (May. 2006), pp.77-93.
https://search.emarefa.net/detail/BIM-24160
American Medical Association (AMA)
al-Helby, A. A.& Musa, Amin& al-Sawwah, M. M.& Bayyumi, A. H.& al-Azab, Adil S.& Sherbiny, F. F.. Synthesis and microbiological testing of some new derivatives of compounds containing active methylene group. Journal of Saudi Chemical Society. 2006. Vol. 10, no. 1, pp.77-93.
https://search.emarefa.net/detail/BIM-24160
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 93
Record ID
BIM-24160