Chromosomal abnormalities associated with recurrent spontaneous abortions in Iraqi women

Abstract EN

Chromosomal analysis is an important etiological investigation in couples with repeated spontaneous abortions as it helps in genetic counseling and deciding about further reproductive options.

Abortions, specially first trimester abortions is a very common complication and a matter of concern for couples planning pregnancy.

Balanced chromosomal rearrangements in either parent is an important cause of recurrent pregnancy loss particularly in the first trimester.

In this study there is an evaluation of the contribution of chromosomal anomalies in causing repeated spontaneous abortions.

To understand the cytogenetic causes in the couples with spontaneous abortions, cytogenetic study was done on 61 couples (122 individuals) with recurrent spontaneous abortions who were examined for chromosomal abnormalities and aberrations.

Women who had at least two abortions, or spontaneous abortions preceded or followed by fetal deaths or birth of a malformed child.

We have found 9.83% of all cases carrying chromosomal aberrations and abnormalities included 7.37% of all cases were structural aberrations & 2.45 of all cases were numerical anomalies.