The immune functions and immune profiles of human bacterial persistent pyuria

Abstract EN

One hundred twenty five uropathy patients were with clinically proven persistent pyuria (PP).

Bacterial culture studies for their clean catch midstream urine samples showed that they were of bacterial causes (BPP).

Mucosal and serum globulin concentrations, specific agglutinins and mucosal as well as peripheral leucocytes inhibition index were made to these patients.

Results of these immunologic investigations have shown that the associated bacterial uropathogens (ABUs) were of both gram negative and gram positive types.

These ABUs may have one or more than one of the antigenic epitopes.

The patient immune responses were dependent on the nature of the immunodominant epitope of the antigen.

Thus antibody responses may be scored alone or antibody and cell mediated responses can be scored among these patients.

Immunocompromy, no matter of its origin reduce the outcome of the immune function.

Five immunoprofiles were deduced as, Profile I : The infection stimulate mucosal and systemic humoral and cellular immune responses.

Profile II : The infection stimulate mucosal and systemic humoral immune rcsponses.

Profile III : The infection stimulate reduced mucosal and systemic humoral and cellular immune respones.

Profile IV : The infection stimulate low grade mucosal and systemic humoral immune responses.

Profile V : The antigen no recoverable with low globulin levels.