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Peroxidase enzyme activity in gingival tissues associated with aggressive periodontitis : histochemical investigation
Other Title(s)
نشاط انزيم البيروكسيديز في أنسجة اللثة المرتبطة التهاب اللثة الشديدة : تحقيق نسيجي .
Joint Authors
al-Azzawi, Lihadh M.
Mirza, Khalid B.
Source
Issue
Vol. 5, Issue 2 (30 Jun. 2008), pp.168-175, 8 p.
Publisher
University of Babylon College of Medicine
Publication Date
2008-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract AR
أثبتت الدراسات الكيميائية الخلوية أن إنزيم البيروكسيديز يساهم بشكل ملحوظ في حركة إنزيمات اللايزوزوم و البروتينات الإفرازية خلال مختلف الممرات الإفرازية.
إنزيم البيروكسيديز الموجود في خلايا الدم البيضاء قد تساعد في تحديد شدة الالتهاب.
عدم فاعلية كرات الدم البيضاء الموجودة في مناطق الالتهاب اللثوي يعود إلى منتجات البكتيريا الموجودة في الصفيحة الجرثومية الغير موجودة في المناطق الخالية من الالتهاب.
Abstract EN
Background: Cytochemical studies on peroxidase have contributed significantly to understanding of the movement of lysosomal enzymes and secretory protein through the various compartments of secretary pathway.
The peroxidase in leukocytes (myeloperoxidase) could help in determining the severity of inflammation.
Aim: To determine the severity of inflammation in gingival tissue associated with aggressive periodontitis by histochemical method and to determine peroxidase enzyme activity semiquantativity.
Material and Method: Five gingival biopsies and five blood smears, three with aggressive periodontitis and two from healthy gingiva.
Histochemical method for peroxidase activity using the technique described by Deimann et al (1991) was used.
Results: sections clearly show a wide and intense distribution of the enzyme activity in gingival tissue with inflammation specifically in the subepithelial connective tissue, while a discrete low activity was obtained in the epithelial tissue.
Control section showed small or few amounts of enzyme activity.
In blood smears from aggressive periodontitis and control showed similar peroxidase activity in the section.
Conclusion: PMNs dysfunction observed in periodontal lesions may be a localized phenomenon caused by plaque bacterial products not found in healthy sites.
American Psychological Association (APA)
al-Azzawi, Lihadh M.& Mirza, Khalid B.. 2008. Peroxidase enzyme activity in gingival tissues associated with aggressive periodontitis : histochemical investigation. Medical Journal of Babylon،Vol. 5, no. 2, pp.168-175.
https://search.emarefa.net/detail/BIM-243136
Modern Language Association (MLA)
al-Azzawi, Lihadh M.& Mirza, Khalid B.. Peroxidase enzyme activity in gingival tissues associated with aggressive periodontitis : histochemical investigation. Medical Journal of Babylon Vol. 5, no. 2 (2008), pp.168-175.
https://search.emarefa.net/detail/BIM-243136
American Medical Association (AMA)
al-Azzawi, Lihadh M.& Mirza, Khalid B.. Peroxidase enzyme activity in gingival tissues associated with aggressive periodontitis : histochemical investigation. Medical Journal of Babylon. 2008. Vol. 5, no. 2, pp.168-175.
https://search.emarefa.net/detail/BIM-243136
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 171-172
Record ID
BIM-243136