Risk factors for progression of chronic kidney disease in diabetic patients

Abstract EN

Background The incidence and progression of renal injury vary substantially among individuals who are at-risk for kidney disease.

Prediction of increased risk of occurrence or progression of CKD enables clinicians to identify individuals who may benefit from closer supervision of care or more intensive disease modifying interventions. Method Between March 2005 and July 2007, 151 patients (69 male, 82 female,) with stage 4) chronic renal failure CRF) defined by a cretonne clearance (Ccr) of 16–30 ml/min(15)from A-format Al-Awsat, and Alsader teaching hospital, all of them had a regular follow-up from baseline Ccr until the end of the follow-up period, or the GFR become <15ml/min, (stage 5 CKD) Results: Serum calcium and hemoglobin were significantly lower in patients whose GFR progressed to stage 5 CKD (group (A)), than in patients did not enter stage 5 CKD( group(B)) , baseline urine protein and erythrocyte sedimentation rate were significantly higher in group (A) than in group (B) .The differences between other parameters between patients of the 2 groups were not significant.

Conclusion: In conclusion our study suggests that baseline hypocalcaemia, anemia, high ESR, and proteinuria are independent predictors for progression of CKD.