Phytolectin induced experimental lapin immunomodulation

Abstract EN

The plant seed extracts of Cucumis.

sativa and Citrullus.

Colocynths are containing glycoprotein molecules described to be of lection characters.

These elections were used as possible immunomodulant.

The test immunogenic was Mycobacterium tuberculosis PPD and the test immune system was the rabbit with the aim of proving of any immunomodulation effects.

The C.

sativa lection (Csl) stimulates the secondary humeral immune response and produce leucocyte Inhibitory cytokines in primary, secondary cell mediated immune responses as well as augmentation of skin DTH reaction in both primary and secondary responses.

The C.eulocvnthus lection (Ccl) was stimulating to primary and secondary humeral immune responses as well as it stimulate production of Leucocyte inhibitory cytokines (LIF) both primary and secondary cell mediated immune responses.

It was however, inhibiting to skin DTH reactions in both primary and secondary responses Thus Csl and Ccl are of immunomodulation potential in rabbits, Immune system affecting both humeral and cellular arms.