The pattern of gastric mucosal cells in peptic ulcer patients

Abstract EN

This study aimed to investigate the pattern of gastric cells count in peptic ulcer patients.

200 patients with peptic ulcer disease were included in this study, 160 of them have Du and 40 of them have GU.

Eighty normal subjects were considered as control group .We had performed gastric astral and gastric body mucosal biopsy for all these patients with peptic ulcer and including the control group in order to study the histopathologically pattern of gastric mucosal cells.

The results, of this study showed that the parietal cells count significantly (P< 0.01) higher in duodenal ulcer patients than normal control group and also significantly lower in gastric ulcer patients than control group.

There was no significant difference in parietal cells counts in peptic ulcer patients weather infected with H-pylori or non-infected with H.

pylori.

Also the chief cells count was significantly (P<0.

05) higher in duodenal ulcer patients than control and was significantly Lower in gastric ulcer patients than control.

H-pylori infection has no effect on chief cells count in Du and Gu patients than control group.

Mucous cells count was significantly (p

patients with peptic ulcer disease infected with H-pylori had Lower mucous cells count than those non infected with H-pylori .There was none–significant difference ( P>0.05) in D-cells and G-cells count between duodenal ulcer patients and control group, but there was a significant decrease in D-cells and Gcells count in gastric ulcer patients than control.

H.

pylori infection has no effect on D-cells and G-cells count in peptic ulcer patients.