Changes of white blood cells in children infected with beta thalassemia (in Babylon)‎

Abstract EN

This study was included the changes that were presented in certain blood characteristics of children suffering from beta thalasemia minor and major, a total number used in this study involved 150 of both healthy children and those affected with beta thalasemia.

As far as for thir ages divided into four groups such as (1 ≤ 3 years, > 3-5 years, > 5-10 years and > 10-14 years).

The changes that presented in hematological parameter were, total white blood cells recorded a significant increase p < 0.05 in both types of beta thalasemia when compared with the normal group, as well as differential white blood cells showed a significant increase p < 0.05 in neutrophel cells and monocytes in both types of beta thalasemia in a comparison with healthy children, but on other hand, other types of white blood cells such as (lymphocytes, basophile cells and eosinophile cells) showed normal values in a comparison with the healthy group.

The changes that are explained may be due to increase bone marrow expansion and its activity.

As well as elevation of activity of reticuo- endothelial system that lead to increase phagocytosis.