Adult disseminated cutaneous langerhans cell histocytosis with nail involvement in a Sudanese patient : a case report and review

Abstract EN

Disseminated cutaneous langerhans cell histocytosis (LCH), are group of rare histiocytic syndromes and idiopathic disorders characterized by the proliferation of specialized bone marrow-derived Langerhans cells (LCs) and mature eosinophils.

We report a case of langerhans cell histocytosis with limited skin and nail involvement occurred in a 26 years old male patient.

The describe case is an undiagnosed and relapsing case of skin and nail limited LCH, presented with erythematous greasy scales in the scalp and discrete, yellow brownish, scaly papules with areas of purpura mainly in face and trunk for 3 years duration, and then remains stable over time.

The case is diagnosed and confirmed histopathologically, considered to be the first disseminated langerhans cell histocytosis in an adult to be reported in Sudan.