Biochemical studies on enrofloxacin and some feed additives commonly used in broiler chicks

Abstract EN

The present study aimed to evaluate the comparative effect of probiotics and some antibiotics on the chicken gut microflora as well as their effect on some biochemical parameters in broiler chicks.

The experiment was carried out on 600 one day old chicks divided into six groups each contain 100 chicks.

The chicks were reared in separated blocks, provided with wood shaving litter, plastic feeders and water troughs.

The birds were fed on a starter ration for the first three weeks and then on a grower ration for the next three weeks and the water was provided continuously.

The serum AST, ALT, uric acid, total protein and albumin were measured.

The results showed elevation in serum AST, ALT, uric acid levels of enrofloxacin treated birds, also revealed hypoproteinaemia and hypoalbuminaemia in the same treated group which indicated pathological changes in liver and kidney of this group.

These changes occurred in less severity in the first weeks of treatment in enramycin treated birds and soon returned to the normal levels.

Meanwhile other treated groups showed normal biochemical results all over the experiment compared to the control.