Intravenous iron sucrose vs. Blood transfusion in the management of symptomatic post partum iron deficiency Anemia
Joint Authors
Tahat, Yusuf A.
Khamaysah, Khaldun
Quran, Fatimah
Shuraydah, Ziyad Ahed
Source
Journal of the Royal Medical Services
Issue
Vol. 18, Issue 1 (31 Mar. 2011), pp.15-19, 5 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2011-03-31
Country of Publication
Jordan
No. of Pages
5
Main Subjects
Topics
Abstract EN
Objective : To compare the efficacy and safety of intravenous iron with blood transfusion in post partum women with symptomatic iron deficiency anaemia.
Methods : Ninety women were included in the study.
The inclusion criteria were : hemoglobin <9g / dl and / or haematocrit <28%, mean corpuscular volume <80fl, ferritin level <15ng / ml, and symptoms of anaemia within 48 hours of delivery.
Women with postpartum haemorrhage and haemodynamic instability were excluded.
Women were divided into two groups, group B received blood transfusion and group I received intravenous iron sucrose (400mg infusion in 250ml Normal Saline over half an hour) (Venofer, Vifor St Gallen's, Switzerland).
The outcome measures were relief of symptoms of anaemia.
Hemoglobin, haematocrit, mean corpuscular volume and ferritin levels were measured before and one week after the treatment.
Results : The two groups were comparable in terms of age, mode of delivery and symptoms.
Group B had a mean age of 31.1 years (22-39) vs.
32.3 years (20-43).
Twenty four women from group B had C / S vs.
23 women in group I.
However, women in group B had a lower baseline mean hemoglobin (6.8 g / dl (4-8) vs.
7.7g / dl (6.1-9 g / dl) and lower haematocrit (23.2 %( 18-26) vs.
25.3 %( 18-28).
At one week post treatment the mean rise in hemoglobin was 2.35 g / dl (34%) in group B vs.
2.15g / dl (27%) in group I.
The mean rise in haematocrit was 7.0 % and 6.3% respectively.
The mean rise in ferritin level was higher in group I (220%) vs.
150% in group B.
Symptoms relief occurred in 29 cases in group B and in 28 cases in group I.
No serious side effects occurred in either group.
Conclusion : Intravenous iron sucrose is an effective and safe treatment for postpartum iron deficiency anaemia.
It is hoped that this treatment will reduce the need for blood transfusion.
American Psychological Association (APA)
Khamaysah, Khaldun& Tahat, Yusuf A.& Shuraydah, Ziyad Ahed& Quran, Fatimah. 2011. Intravenous iron sucrose vs. Blood transfusion in the management of symptomatic post partum iron deficiency Anemia. Journal of the Royal Medical Services،Vol. 18, no. 1, pp.15-19.
https://search.emarefa.net/detail/BIM-249798
Modern Language Association (MLA)
Shuraydah, Ziyad Ahed…[et al.]. Intravenous iron sucrose vs. Blood transfusion in the management of symptomatic post partum iron deficiency Anemia. Journal of the Royal Medical Services Vol. 18, no. 1 (Mar. 2011), pp.15-19.
https://search.emarefa.net/detail/BIM-249798
American Medical Association (AMA)
Khamaysah, Khaldun& Tahat, Yusuf A.& Shuraydah, Ziyad Ahed& Quran, Fatimah. Intravenous iron sucrose vs. Blood transfusion in the management of symptomatic post partum iron deficiency Anemia. Journal of the Royal Medical Services. 2011. Vol. 18, no. 1, pp.15-19.
https://search.emarefa.net/detail/BIM-249798
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 19
Record ID
BIM-249798