Synthesis and antimicrobial activity of some new quinazolin-4(3)-one derivatives
Author
Source
Journal of Saudi Chemical Society
Issue
Vol. 15, Issue 2 (30 Apr. 2011), pp.95-100, 6 p.
Publisher
Publication Date
2011-04-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
A new series of 6-iodo-2-phenylquinazolin-4(3H)-one derivatives was prepared and screened for antimicrobial activity.
The thioureide derivatives 4-6, the carbohydrazide derivatives 19-21 and 24 displayed excellent broad-spectrum antimicrobial activity.
Some compounds showed moderate activity against Candida albicans and Pseudomonas aeruginosa.
None of the tested compounds was as active as the reference standard drugs ampicillin and clotrimazole.
The detailed synthesis, antimicrobial activity, and the minimum inhibitory concentrations (MIC) are reported.
American Psychological Association (APA)
Qadi, Adnan A.. 2011. Synthesis and antimicrobial activity of some new quinazolin-4(3)-one derivatives. Journal of Saudi Chemical Society،Vol. 15, no. 2, pp.95-100.
https://search.emarefa.net/detail/BIM-250177
Modern Language Association (MLA)
Qadi, Adnan A.. Synthesis and antimicrobial activity of some new quinazolin-4(3)-one derivatives. Journal of Saudi Chemical Society Vol. 15, no. 2 (Apr. 2011), pp.95-100.
https://search.emarefa.net/detail/BIM-250177
American Medical Association (AMA)
Qadi, Adnan A.. Synthesis and antimicrobial activity of some new quinazolin-4(3)-one derivatives. Journal of Saudi Chemical Society. 2011. Vol. 15, no. 2, pp.95-100.
https://search.emarefa.net/detail/BIM-250177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 100
Record ID
BIM-250177