Anti-ulcer activity of Smithia conferta in various animal
Joint Authors
Agrawal, Rajiv
Garg, H. K.
Garg, Udita
Singh, S. K.
Source
Journal of Saudi Chemical Society
Issue
Vol. 14, Issue 3 (30 Sep. 2010), pp.307-310, 4 p.
Publisher
Publication Date
2010-09-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Smithia conferta Sm.
(Leguminasae), is a commonly used plant in Indian traditional medicine.
In the current study anti-ulcer activity of its petroleum ether, alcohol and aqueous extracts of leaves were investigated using different animal models.
All extracts were also subjected to phytochemical analysis and their toxic potential.
Petroleum ether extract was found to contain steroids; alcohol extract revealed the presence of isoflavonoids, alkaloids and carbohydrates; while aqueous extract was found to contain amino acids, carbohydrates and flavonoids.
S.
conferta aqueous and alcoholic extracts were found to be non-toxic up to 5000 mg / kg dose level while petroleum ether extract was safe only up to a dose of 2000 mg / kg after single dose administration of the extracts.
During confirmation of the claimed anti-ulcer activity, treatment with aqueous and alcoholic extracts showed significant reduction in ulcer index, free acidity as well as total acidity in pylorus ligated rats.
However, petroleum ether extract showed relatively less profound reduction in all these indices.
The anti-ulcer activity observed in aqueous extract treatment group was nearly equivalent to the standard group.
American Psychological Association (APA)
Agrawal, Rajiv& Garg, H. K.& Garg, Udita& Singh, S. K.. 2010. Anti-ulcer activity of Smithia conferta in various animal. Journal of Saudi Chemical Society،Vol. 14, no. 3, pp.307-310.
https://search.emarefa.net/detail/BIM-250551
Modern Language Association (MLA)
Agrawal, Rajiv…[et al.]. Anti-ulcer activity of Smithia conferta in various animal. Journal of Saudi Chemical Society Vol. 14, no. 3 (Sep. 2010), pp.307-310.
https://search.emarefa.net/detail/BIM-250551
American Medical Association (AMA)
Agrawal, Rajiv& Garg, H. K.& Garg, Udita& Singh, S. K.. Anti-ulcer activity of Smithia conferta in various animal. Journal of Saudi Chemical Society. 2010. Vol. 14, no. 3, pp.307-310.
https://search.emarefa.net/detail/BIM-250551
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 310
Record ID
BIM-250551