Molecular modeling of 8-methoxy quinolone analogues by using quantitative structure activity relationship

Joint Authors

Srivastava, A. K.
Pathak, Vinay Kumar
Srivastava, Akanchha
Pandey, Avni

Source

Journal of Saudi Chemical Society

Issue

Vol. 14, Issue 2 (30 Jun. 2010), pp.217-222, 6 p.

Publisher

Saudi Chemical Society

Publication Date

2010-06-30

Country of Publication

Saudi Arabia

No. of Pages

6

Main Subjects

Chemistry

Abstract EN

Quantitative structure activity relationship (QSAR) studies on a series of 8-methoxy quinolone are found to correlate well with steric parameters and electronic parameter.

The results are critically discussed on the basis of regression data, Polanyi factor Q and cross validation technique.

The results are found to be useful in discussing the mechanism of drug - receptor interaction.

Steric parameter 'Mr' and electronic parameter 'Pz' gives the best model.

American Psychological Association (APA)

Srivastava, A. K.& Pathak, Vinay Kumar& Srivastava, Akanchha& Pandey, Avni. 2010. Molecular modeling of 8-methoxy quinolone analogues by using quantitative structure activity relationship. Journal of Saudi Chemical Society،Vol. 14, no. 2, pp.217-222.
https://search.emarefa.net/detail/BIM-250607

Modern Language Association (MLA)

Srivastava, A. K.…[et al.]. Molecular modeling of 8-methoxy quinolone analogues by using quantitative structure activity relationship. Journal of Saudi Chemical Society (Jun. 2010), pp.217-222.
https://search.emarefa.net/detail/BIM-250607

American Medical Association (AMA)

Srivastava, A. K.& Pathak, Vinay Kumar& Srivastava, Akanchha& Pandey, Avni. Molecular modeling of 8-methoxy quinolone analogues by using quantitative structure activity relationship. Journal of Saudi Chemical Society. 2010. Vol. 14, no. 2, pp.217-222.
https://search.emarefa.net/detail/BIM-250607

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 222

Record ID

BIM-250607