Spectrophotometric and titrimetric methods for the determination of nordiazepam in pure and pharmaceutical dosage form
Joint Authors
Mustafa, N. M.
al-Gohani, E. H.
Source
Journal of Saudi Chemical Society
Issue
Vol. 14, Issue 1 (31 Mar. 2010), pp.9-13, 5 p.
Publisher
Publication Date
2010-03-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
A spectrophotometric method and two titrimetric methods for the determination of nor diazepam via its iodobismuthate complex are described.
These methods depend on the reaction of nor diazepam with potassium bismuth iodide which give an orange precipitate.
Determination of nor diazepam in the precipitated complex is done eudiometrically using standard potassium iodate solution or complex metrically using standard EDTA solution and xylenol orange indicator.
Alternatively, the complex is dissolved in ethanol and its absorbance is measured at 323 nm.
The three methods were applied for the determination of reference samples of nor diazepam in the concentration range of 1-30 mg ml-1 (for the iodometric method) and of 5-30 mg ml-1 (for the complexomet-ric method) and of 0.04-3.2 mgrnl-1 (for the spectrophotometric method).
The proposed methods were applied for the determination of nor diazepam in madar tablets and the validity of the proposed methods was assessed by applying the standard addition technique.
American Psychological Association (APA)
Mustafa, N. M.& al-Gohani, E. H.. 2010. Spectrophotometric and titrimetric methods for the determination of nordiazepam in pure and pharmaceutical dosage form. Journal of Saudi Chemical Society،Vol. 14, no. 1, pp.9-13.
https://search.emarefa.net/detail/BIM-250650
Modern Language Association (MLA)
Mustafa, N. M.& al-Gohani, E. H.. Spectrophotometric and titrimetric methods for the determination of nordiazepam in pure and pharmaceutical dosage form. Journal of Saudi Chemical Society (Mar. 2010), pp.9-13.
https://search.emarefa.net/detail/BIM-250650
American Medical Association (AMA)
Mustafa, N. M.& al-Gohani, E. H.. Spectrophotometric and titrimetric methods for the determination of nordiazepam in pure and pharmaceutical dosage form. Journal of Saudi Chemical Society. 2010. Vol. 14, no. 1, pp.9-13.
https://search.emarefa.net/detail/BIM-250650
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 12-13
Record ID
BIM-250650