A novel antimicrobial triterpenic acid from the leaves of ficus benjamina (var. comosa)‎

Abstract EN

The chloroform extract of the leaves of Ficus benjamina (var.

comosd) (Moraceae) afforded a new triterpenic acid named as (9, 11), (18, 19)-disecoolean-12-en-28-oic acid (1) along with P-amyrin (2).

Their structures were established on the basis of chemical and physical evidences (IR, 'H NMR, and MS data).

The compound 1 exhibited significant antimicrobial activity against Salmonella typhimurium (MTCC-98), Candida albicans (IAO-109), Staphylococcus aureus (IAO-SA-22), Escherichia coli (K-12) and low activity against Aspergillums Niger (lab isolate ICAR) and Aspergillums brassicola.