Helicobacter pylori resistance to metronidazole and clarithromycin in dyspeptic patients in Iran
Joint Authors
Tomatari, F. Haghi
Mobarez, A. Mohabbati
Amini, M.
Hosseini, D.
Abbadi, A. Talebi Bezmin
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 12, Issue 4 (31 Jul. 2010), pp.409-412, 4 p.
Publisher
Publication Date
2010-07-31
Country of Publication
United Arab Emirates
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background : the resistance of H.
pylori to the recently available antibiotic treatment regimens has been a growing problem.
The prevalence of high antibiotic resistance of H.
pylori is the most common reason of its eradication failure.
The purpose of the present study is to determine the prevalence of antibiotic resistance among H.
pylori strains isolated from Iranian patients.
Method : we investigated the prevalence of H.
pylori resistance to metronidazole, clarithromycin, amoxicillin, and tetracycline among 128 H.
pylori isolates from Iranian patients.
After the culture of biopsy specimens and identification, susceptibility tests was performed with Modified Disk Diffusion Method (MDDM) and E.
test.
Results : resistance rates to metronidazole, clarithromycin, amoxicillin and tetracycline were 64 %, 23 %, 2.5 % and 0 %, respectively.
Seventy two percent of the metronidazole resistance strains had MIC > 256g / ml (High-Level-Resistance).
Discussion : due to the increasing rate of antibiotic resistance in H.
pylori strains and in order to decrease the treatment cost, testing of susceptibility to metronidazole and clarithromycin is recommended.
American Psychological Association (APA)
Tomatari, F. Haghi& Mobarez, A. Mohabbati& Amini, M.& Hosseini, D.& Abbadi, A. Talebi Bezmin. 2010. Helicobacter pylori resistance to metronidazole and clarithromycin in dyspeptic patients in Iran. Iranian Red Crescent Medical Journal،Vol. 12, no. 4, pp.409-412.
https://search.emarefa.net/detail/BIM-252398
Modern Language Association (MLA)
Tomatari, F. Haghi…[et al.]. Helicobacter pylori resistance to metronidazole and clarithromycin in dyspeptic patients in Iran. Iranian Red Crescent Medical Journal Vol. 12, no. 4 (Jul. 2010), pp.409-412.
https://search.emarefa.net/detail/BIM-252398
American Medical Association (AMA)
Tomatari, F. Haghi& Mobarez, A. Mohabbati& Amini, M.& Hosseini, D.& Abbadi, A. Talebi Bezmin. Helicobacter pylori resistance to metronidazole and clarithromycin in dyspeptic patients in Iran. Iranian Red Crescent Medical Journal. 2010. Vol. 12, no. 4, pp.409-412.
https://search.emarefa.net/detail/BIM-252398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 412
Record ID
BIM-252398