Effect of hyperprolactinaemia on concentration of immunoglobulins and complement components in a series of infertile Iraqi women

Abstract EN

The present study was designed to detection the immunoglobulin's concentration and complement component effects by hyperprolactinaemia The sample included i < patients, who were attending the Institute for Embryo Research and Infertility Treatment for diagnosis and treatment In Bagdad city during the period 200v-April-to-200v-Septemper.

Primary infertile females patients with hyperprolactinaemia (age range : 20-40 years) were investigated.

The collected serum was tested for the determination of prolactin levels using a minivans system, (serum level of prolactin >* ng / m1), the total patients were divided into three groups; I (* > patients).

II (Y ipatients) and III 0 *patients), Their serum prolacin levels were 22-29, 30-39 and > 40 ng / ml, respectively.

single radial immunodiffusion test).

Used to Quantitative Measurement of Immunoglobulin's (lgA, lgG and 1gM) and Complement components C3 and C4 which was developed by( Mancini et al.

1965).

The immunoglobulin's (lgA, IgG and IgM) showed a significant increased total level in the sera of total patients when compared with controls, (265.5 vs.

225.3, 1423 vs.

1 076 and 266 vs.

188 mg / d1.

Respectively..

With respect to complement components, the serum levels of C3 and C4 were slightly decreased in the patients, but the difference did not reach a statistical level.