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Electron microscopic study of the effects of preeclampsia on the placental endothelial cells ultra structures during pregnancy
Joint Authors
al-Kasi, Kawkab Salim
al-Habib, Mayy Fadl
Abd al-Shahid, Nahid Aday
Source
al-Kindy College Medical Journal
Issue
Vol. 6, Issue 1 (30 Jun. 2010), pp.39-44, 6 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2010-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Preeclampsia occurs in 3-5% of pregnancies and is a major cause (12-20 %) of maternal mortality in developed countries.
It is the leading cause of preterm birth and intra-uterine growth restrictions (IUGR).
Objective : The study was designed to determine and demonstrate the ultra structural changes of endothelial cells in placenta of women suffering from hypertensive disease.
Methods : Placental samples were obtained from two groups of pregnant women groups (preeclamptic and normal pregnant women).
The specimens were fixed in 2.5% gluteraldehyde and preceded for electron microscopic examination.
Results : Placenta of women with preeclampsia has shown marked degenerative changes in both endothelial and trophoblastic cells.
These changes were represented by precipitation of fibrin with the accumulation of platelets in capillary lumen.
Abundance of collagen fibers precipitate in the apical region of both endothelial cells and trophoblasts, with thickening of endothelial basement membrane.
Conclusion : All histological changes or lesions obstruct the continuous conduction from maternal surface of the trophoblasts through fetal capillary endothelium causing endothelial dysfunction.
American Psychological Association (APA)
al-Kasi, Kawkab Salim& al-Habib, Mayy Fadl& Abd al-Shahid, Nahid Aday. 2010. Electron microscopic study of the effects of preeclampsia on the placental endothelial cells ultra structures during pregnancy. al-Kindy College Medical Journal،Vol. 6, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-256845
Modern Language Association (MLA)
al-Kasi, Kawkab Salim…[et al.]. Electron microscopic study of the effects of preeclampsia on the placental endothelial cells ultra structures during pregnancy. al-Kindy College Medical Journal Vol. 6, no. 1 (Jun. 2010), pp.39-44.
https://search.emarefa.net/detail/BIM-256845
American Medical Association (AMA)
al-Kasi, Kawkab Salim& al-Habib, Mayy Fadl& Abd al-Shahid, Nahid Aday. Electron microscopic study of the effects of preeclampsia on the placental endothelial cells ultra structures during pregnancy. al-Kindy College Medical Journal. 2010. Vol. 6, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-256845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 43-44
Record ID
BIM-256845