Follow-up study of bone mineral density and c-terminal telopeptide marker as predicators of fracture risk
Joint Authors
Abd al-Rahman, Samiyah Ahmad
Hafiz, Iman Ahmad
Umar, Husayn Umar
Shahin, Karim Yahya
Murtaji, Ahmad kamel
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 36, Issue 2 (30 Apr. 2009), pp.165-179, 15 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
2009-04-30
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Background: Osteoporosis is a major health problem in many countries.
Osteoporotic fractures are the main consequence of osteoporosis.
Objective: Our aim was to identify the usefulness of bone mineral density and C-terminal telopeptide of type 1 collagen as predictors of fracture risk.
Methodology: We evaluated both BMD and serum carboxy-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) in 212 subjects recruited from the community.
This included healthy postmenopausal women and males over 60 years.
Subjects were followed up for the occurrence of fractures for one year.
X-ray radiographs of thoracic and lumber regions were done to detect silent vertebral fractures at baseline, and at the end of 1 year.
Results and conclusions Male gender was associated with a higher level of serum ICTP.
BMD was insignificantly higher in males compared with females.
Age, weight, BMI were significantly correlated with BMD.
Age was significantly correlated with ICTP levels.
BMD proved to be a strong predictor of incident fracture specially vertebral and hip fractures.
Serum levels of ICTP were also predictors of incident fracture and this observation was more evident in females compared to males.
Advancing age and low weight were predictors of increased incidence of fractures.
Coffee was found to increases bone resorption, accordingly has a detrimental effect on bone strength.
Other caffeine containing beverages (tea, cola) were not fond to have a significant effect on bone resorption.
American Psychological Association (APA)
Abd al-Rahman, Samiyah Ahmad& Hafiz, Iman Ahmad& Umar, Husayn Umar& Shahin, Karim Yahya& Murtaji, Ahmad kamel. 2009. Follow-up study of bone mineral density and c-terminal telopeptide marker as predicators of fracture risk. Egyptian Rheumatology and Rehabilitation،Vol. 36, no. 2, pp.165-179.
https://search.emarefa.net/detail/BIM-258253
Modern Language Association (MLA)
Abd al-Rahman, Samiyah Ahmad…[et al.]. Follow-up study of bone mineral density and c-terminal telopeptide marker as predicators of fracture risk. Egyptian Rheumatology and Rehabilitation Vol. 36, no. 2 (Apr. 2009), pp.165-179.
https://search.emarefa.net/detail/BIM-258253
American Medical Association (AMA)
Abd al-Rahman, Samiyah Ahmad& Hafiz, Iman Ahmad& Umar, Husayn Umar& Shahin, Karim Yahya& Murtaji, Ahmad kamel. Follow-up study of bone mineral density and c-terminal telopeptide marker as predicators of fracture risk. Egyptian Rheumatology and Rehabilitation. 2009. Vol. 36, no. 2, pp.165-179.
https://search.emarefa.net/detail/BIM-258253
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 178-179
Record ID
BIM-258253