Dextran instead of adrenaline to prolong the duration of action of the local anesthetic in high risk patients

Abstract EN

This study was designed to investigate the efficacy of 40000MW dextran instead of adrenalin in prolongation of the duration of action of local anesthesia in high risk patients.

Surgery was performed under local anesthesia, lignocaine 2%with either dextran 40000 MW or adrenaline, sciatic nerve and three in one block.

The results showed no significant variations between the duration of action when the lignocaine 2% used with dextran or adrenaline.

Accordingly, dextran is a good alternative for adrenaline in prolongation of local anesthesia in high risk patients.