الفعالية الضد مايكروبية لمستخلص الحنظل و السذاب و الكركم مختبرياً

Abstract EN

This study was Prepared for evaluate the efficiency of acidic- water, ethanolic and butanolic plant extracts for three medicinal plants are : Citrullus colocynthis L., Ruta chalepensis L.

and Curcuma longa Roxb.

Against four bacterial and fungal isolates in three concentrations : 500 mg / ml, 250 mg / ml and 125 mg / ml by agar well diffusion assays.

The results showed that the highest inhibition zone diameters (25 mm) in concentration 500 mg / ml for acidic-water extract of fruits Citrullus colocynthis L against Candida albicans ; while the acidic-water extract of leaves Ruta chalepensis L appeared highest inhibition zone diameters (41 mm) in the same concentration against gram positive bacteria Staphylococcus aureus.

Also it has been detected about active compounds in all plant extracts beside of isolation alkaloids and phenolic compounds and the antimicrobial activity was tested in three concentrations : 200 mg / ml, 100 mg / ml and 50 mg / ml, the results showed the alkaloids and phenolic compounds were not appeared any antimicrobial activity.

Apart from cytotoxicity for all plant extracts in concentration 500 mg / ml determined against Red Blood Cells ; and there was no sign toxicity appeared against it.