Evaluation of antinociceptive effect of tramadol in chicks

Other Title(s)

دراسة التأثير المسكن للترامادول في أفراخ الدجاج

Joint Authors

Tawfiq, Nahla Uthman Muhammad
al-Ṣunduq, Tahani Abd al-Aziz
Taqah, Ghadah Abd al-Rahman

Source

المجلة العراقية للعلوم البيطرية

Publisher

University of Mosul College of Veterinary Medicine

Publication Date

2009-12-31

Country of Publication

Iraq

No. of Pages

4

Main Subjects

Biology

Topics

• Physiology
• Pain
• Analgesics
• Anaesthesia

English Abstract

In this study the ED50 of tramadol was evaluated and it was found to be equal to (0.85 mg/kg).

The analgesic effect of tramadol (1 mg/kg) by subcutaneous route was investigated in chicks by using electrical stimulator.

The drug induce a safe and effective analgesia within 30 minute and lasted for 90 minute after injection.

Tramadol also produce sedative effect within 40 minute after administration and last up to 80 minute, presented by dropping of the head and wings, ataxia, lying but able to rise and recumbency then loss of consciousness.

The administration of tramadol produce a dose- depended antinociceptive effect with 10 mg/kg as maximum effective dose.

This study concluded that tramadol have a good analgesic activity in chicks.

Data Type

Conference Papers

Record ID

BIM-260691

• APA
• MLA
• AMA