Cholestatic jaundice in a sample of Iraqi Infants : (a hospital based study)‎

Abstract EN

Background : Cholestasis Jaundice is a dilemma facing not only the primary care provider but alsc specialist pediatricians in our country.

Subjects & methods : analysis of 50 cases of cholestasis jaundice aged 3 weeks-18 months were ca out over 18 months in the Gastroenterology & Hematology unit in the Children Welfare Teaching Hos Medical City, and Baghdad.

Clinical, biochemical, radiological and histopathologically results were recorded.

Results: Fifty patients with Cholestasis Jaundice, 28 males &22 females, were evaluated.

The main causes of Cholestasis Jaundice were Biliary Atresia in 22 cases (44 %) the mean age of presentation was 4.1 months , and Neonatal Hepatitis Syndrome of different etiology in 17 cases (34 %) (The mean age of presentation was 5.9 months).

Galactosemia was the most common cause of metabolic liver disease and CMV was the commonest of the intrauterine viral infections.

Two cases of choledocal cyst (4 %) and no definite was found in 9 cases (18 %) Conclusion : biliary atresia was the most common cause of cholestasis in this study of extra-h type.

Different stages of cirrhosis were found in almost all cases of biliary Atresia because of ds presentation.

Clay color stool, hepatomegaly, high alkaline phosphatase & high cholesterol level atresia cases.

Ultrasonography & liver biopsy prove to be very valuable tools in the differentiation be Biliary Atresia & Neonatal Hepatitis Syndrome.