Progressive osseous heteroplasia (POH) : an Egyptian patient
Joint Authors
al-Shubaki, Izzat
al-Sayyid, Sulaf M.
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 11, Issue 1 (31 May. 2010), pp.79-83, 5 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2010-05-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Progressive osseous heteroplasia is a rare genetic disorder characterized by cutaneous ossification during infancy and progressive ossification of subcutaneous and deep connective tissue including muscle and fascia during childhood.
It is at the severe end of a spectrum of Guanine Nucleotide-binding protein, Alpha-Stimulating activity polypeptide (GNAS) associated ossification disorders that include osteoma cutis and Albright hereditary osteodystrophy.
Here we describe a five year old boy with progressive ossification of skin and subcutaneous tissue and progressive limitation of movement of all joints.
X-rays revealed extensive calcification of cutaneous and subcutaneous tissues involving nearly the whole body.
As far as our knowledge, no cases have been reported before in the Middle East.
Here we describe the first Egyptian child affected with this disorder.
American Psychological Association (APA)
al-Shubaki, Izzat& al-Sayyid, Sulaf M.. 2010. Progressive osseous heteroplasia (POH) : an Egyptian patient. The Egyptian Journal of Medical Human Genetics،Vol. 11, no. 1, pp.79-83.
https://search.emarefa.net/detail/BIM-262143
Modern Language Association (MLA)
al-Shubaki, Izzat& al-Sayyid, Sulaf M.. Progressive osseous heteroplasia (POH) : an Egyptian patient. The Egyptian Journal of Medical Human Genetics Vol. 11, no. 1 (May. 2010), pp.79-83.
https://search.emarefa.net/detail/BIM-262143
American Medical Association (AMA)
al-Shubaki, Izzat& al-Sayyid, Sulaf M.. Progressive osseous heteroplasia (POH) : an Egyptian patient. The Egyptian Journal of Medical Human Genetics. 2010. Vol. 11, no. 1, pp.79-83.
https://search.emarefa.net/detail/BIM-262143
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 82-83
Record ID
BIM-262143