Effect of ultraviolet radiation on the spermatogenesis and testes of albino swiss mice

Abstract EN

The effect of different wavelengths of ultraviolet (UV) radiation for different periods (2, 5, 10 and 15 days) on testes of albino Swiss mice was investigated.

Results revealed that animals exposed to different periods suffered considerable changes in sperm parameters.

Radiation-induced damage was extended to different testicular tissues including the seminiferous tubules, basement membranes and germ cells.

Reduced sperm count associated with increased percentage of sperm abnormality and sperm death was also shown in UV-irradiated groups as compared with controls.

It was found that when UV wavelength decreased from 366 to 254 nm and the exposure period increased, this resulted in decreased sperm count, increased percentage of sperm abnormalities and death with more pronounced tissue damage.

The data demonstrates significant ongoing damaging effects of UV radiation on male mice reproductive system with evidence of necrosis and deformation in all developmental sperm stages.