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Synthesis of fused pyrimidines and purines by vicarious nucleophilic substitution of hydrogen (a micro review)
Author
Source
Issue
Vol. 4, Issue 1 (31 Mar. 2009), pp.1-15, 15 p.
Publisher
Yarmouk University Deanship of Research and Graduate Studies
Publication Date
2009-03-31
Country of Publication
Jordan
No. of Pages
15
Main Subjects
Abstract EN
Fused pyrimidine's can be easily synthesized from the corresponding ortho-aminobenzylamine derivatives or their heteroanalogues.
Often the limiting factor for the above syntheses is the difficulty encountered in obtaining the key intermediates or their precursors.
Recently, this problem was successfully solved in several ways by the use of vicarious nucleophile substitution of hydrogen (VNS).
As a result, many quinolones and new bicyclic and tricyclic heteroaromatic compounds and their mono-N-oxides were obtained, when starting from nitroarenes.
These approaches were also successfully applied to the synthesis of purines with the use of 4-nitroimidazole derivatives.
American Psychological Association (APA)
Ostrowski, Stanisław. 2009. Synthesis of fused pyrimidines and purines by vicarious nucleophilic substitution of hydrogen (a micro review). Jordan Journal of Chemistry،Vol. 4, no. 1, pp.1-15.
https://search.emarefa.net/detail/BIM-266460
Modern Language Association (MLA)
Ostrowski, Stanisław. Synthesis of fused pyrimidines and purines by vicarious nucleophilic substitution of hydrogen (a micro review). Jordan Journal of Chemistry Vol. 4, no. 1 (Mar. 2009), pp.1-15.
https://search.emarefa.net/detail/BIM-266460
American Medical Association (AMA)
Ostrowski, Stanisław. Synthesis of fused pyrimidines and purines by vicarious nucleophilic substitution of hydrogen (a micro review). Jordan Journal of Chemistry. 2009. Vol. 4, no. 1, pp.1-15.
https://search.emarefa.net/detail/BIM-266460
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 13-15
Record ID
BIM-266460