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Sublingual versus vaginal misoprostol for cervical priming in early missed abortion
Other Title(s)
إختيار و إعطاء الميزوبروستول عن طريق المهبل أو تحت اللسان لتحفيز و تحضير عنق الرحم في حالات الإجهاض المبكر
Joint Authors
Harb, Hashim Muhammad
al-Shirbini, Muhammad M.
Source
Issue
Vol. 2010, Issue 35 (30 Jun. 2010), pp.50-64, 15 p.
Publisher
Al-Azhar University International Islamic Center for Population Studies and Research
Publication Date
2010-06-30
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Topics
Abstract AR
تضمنت الدراسة 80 حالة تم تقسيمهم على مجموعتين، مجموعة (أ) 40 حالة تلقوا العقار عن طريق المهبل مجموعة (ب) 40 حالة تم إعطائهم العلاج عن طريق الفم (تحت اللسان) تم إعطاء كل حالة قرصين (400 ميكروجرام) من العقار قبل إعطاء عملية التفريغ.
النتائج : أثبتت الدراسة أن إعطاء عقار الميزوبروستول عن طريق تحت اللسان يعطي نفس النتائج التي يعطيها العقار عن إعطائه عن طريق المهبل، و بدون زيادة معدل المضاعفات، كما يمكن إعطاء العقار بالمنزل قبل الذهاب إلى المستشفى و يسهل عملية التفريغ كما أن تقبل لدى المرضى أعلى من عند إعطائه عن طريق الفم.
Abstract EN
Cervical priming has been shown to result in a shorter operative time, less blood loss and easier mechanical dilation, and these may reduce the incidence of complications associated with surgical management of abortion including cervical injury, uterine perforation, hemorrhage and incomplete abortion.
Both vaginal and oral administrations of misoprostol were found to be effective.
However, oral administration avoids vaginal examination in a busy day-surgery admission clinic.
Aim of the work : was to compare the effect of sublingual versus vaginal administration of misoprostol for pre-operative cervical priming before surgical termination of pregnancy in first trimester missed abortion.
Patients : the study comprised 80 patients who were divided into two groups : Group I (40 patients) who received misoprostol by vaginal route while group II (40 patients) who received misoprostol by sublingual route.
Methods : each patient was given 400 / ig misoprostol (2 tablets cytotec®) 4 hours before vacuum aspiration either vaginally (group I) or sublingually (group II).
Results : the use of sublingual misoprostol was as effective in preoperative cervical ripening as vaginal misoprostol.
It was associated with easy cervical dilation in 77.5 % of patients (31 patients from 40 total), versus easy dilation in 82.5 % of patients (33 patients from 40 total) with vaginal misoprostol.
Sublingual misoprostol did not increase the side effects of misoprostol than vaginal route.
Conclusion : sublingual route is an effective and convenient alternative to vaginal administration of misoprostol for cervical ripening and dilation.
It can be conveniently self-administered at home thereby decreasing hospital stay and cost.
It also has a good patient acceptability rate.
American Psychological Association (APA)
al-Shirbini, Muhammad M.& Harb, Hashim Muhammad. 2010. Sublingual versus vaginal misoprostol for cervical priming in early missed abortion. Population Sciences،Vol. 2010, no. 35, pp.50-64.
https://search.emarefa.net/detail/BIM-267798
Modern Language Association (MLA)
al-Shirbini, Muhammad M.& Harb, Hashim Muhammad. Sublingual versus vaginal misoprostol for cervical priming in early missed abortion. Population Sciences No. 35 (2010), pp.50-64.
https://search.emarefa.net/detail/BIM-267798
American Medical Association (AMA)
al-Shirbini, Muhammad M.& Harb, Hashim Muhammad. Sublingual versus vaginal misoprostol for cervical priming in early missed abortion. Population Sciences. 2010. Vol. 2010, no. 35, pp.50-64.
https://search.emarefa.net/detail/BIM-267798
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 63
Record ID
BIM-267798