Effect of metformin on serum ferreting level in women with polycystic ovary syndrome
Joint Authors
Behradmanesh, Saeed
Umrani, Ghulam Husayn Ranjbar
Ghazanfarpour, Faridah
Baradaran, Azar
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 13, Issue 7 (31 Jul. 2011), pp.487-492, 6 p.
Publisher
Publication Date
2011-07-31
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Abstract EN
Background : polycystic ovary syndrome (PCOS) is one of the most common diseases among women associated with various inflammatory reactants such as C-reactive protein (CRP) and ferritin.
This study aimed to investigate the effect of metformin on probable reduction of serum ferritin in patients with PCOS.
Methods : this study was conducted on 45 patients with PCOS who had no other systemic diseases and did not take any medications.
Weight, waist and hip circumstances (WHR), body mass index (BMI), metabolic indexes, CRP, ferritin and “Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) ˝ were measured before the study.
Metformin (500 mg / tid) tablets were prescribed for three months and then same above parameters were re-measured.
Results : of 45 patients, 19 (42.2%) were overweight and 14 (31.1%) were obese.
After drug therapy, there was a significant reduction in waist circumstance and serum ferritin.
This reduction was significant only in the lean and overweight groups but not in the obese group.
There was not significant association between serum ferritin and CRP, HOMA-IR, BMI and WHR.
There was not significant correlation between CRP and HOMA-IR and also BMI.
Conclusion : the effect of metformin on reduction of serum ferritin was not significant just in obese group and was not associated with metabolic and anthropometric indexes.
American Psychological Association (APA)
Behradmanesh, Saeed& Umrani, Ghulam Husayn Ranjbar& Ghazanfarpour, Faridah& Baradaran, Azar. 2011. Effect of metformin on serum ferreting level in women with polycystic ovary syndrome. Iranian Red Crescent Medical Journal،Vol. 13, no. 7, pp.487-492.
https://search.emarefa.net/detail/BIM-268111
Modern Language Association (MLA)
Behradmanesh, Saeed…[et al.]. Effect of metformin on serum ferreting level in women with polycystic ovary syndrome. Iranian Red Crescent Medical Journal Vol. 13, no. 7 (Jul. 2011), pp.487-492.
https://search.emarefa.net/detail/BIM-268111
American Medical Association (AMA)
Behradmanesh, Saeed& Umrani, Ghulam Husayn Ranjbar& Ghazanfarpour, Faridah& Baradaran, Azar. Effect of metformin on serum ferreting level in women with polycystic ovary syndrome. Iranian Red Crescent Medical Journal. 2011. Vol. 13, no. 7, pp.487-492.
https://search.emarefa.net/detail/BIM-268111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 491-492
Record ID
BIM-268111