Beta thalassemia major : the effect of age on glomerular filtration rate
Joint Authors
Maliki, Majid
Sorkhabi, Rohangiz Sari
Shoaran, Maryam
Shafighe, Bagheri
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 22, Issue 5 (31 Oct. 2011), pp.963-968, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2011-10-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Thalassemia is a common hereditary hemoglobinopathy disorder that affects many organs in the body.
Estimation of kidney function is important, as it is the vital organ that plays the major role in the elimination of accumulated iron as well as the chelating drugs that have to be used as therapy.
Sixty-three patients aged 1-29 years, with a mean ± SD of 14 ± 6.7 years, affected with beta-thalassemia major in Tabriz Children’s Hospital were evaluated for their renal function on the basis of their age, serum iron, serum ferritin and serum cretonne levels along with two methods of estimating glomerular filtration rate (GFR); by Schwartz method for those under 18 years old and using Modification of Diet in Renal Disease (MDRD) formula for those who were 18 years and above.
Elevation of serum cretonne denoting renal dysfunction was not seen in our patients, but hyper filtration was a common finding.
An increasing GFR was observed, which corresponded to age, but no relationships were seen between serum iron, serum ferritin, regular blood transfusion, chelating therapy to GFR.
American Psychological Association (APA)
Maliki, Majid& Sorkhabi, Rohangiz Sari& Shoaran, Maryam& Shafighe, Bagheri. 2011. Beta thalassemia major : the effect of age on glomerular filtration rate. Saudi Journal of Kidney Diseases and Transplantation،Vol. 22, no. 5, pp.963-968.
https://search.emarefa.net/detail/BIM-268122
Modern Language Association (MLA)
Maliki, Majid…[et al.]. Beta thalassemia major : the effect of age on glomerular filtration rate. Saudi Journal of Kidney Diseases and Transplantation Vol. 22, no. 5 (Oct. 2011), pp.963-968.
https://search.emarefa.net/detail/BIM-268122
American Medical Association (AMA)
Maliki, Majid& Sorkhabi, Rohangiz Sari& Shoaran, Maryam& Shafighe, Bagheri. Beta thalassemia major : the effect of age on glomerular filtration rate. Saudi Journal of Kidney Diseases and Transplantation. 2011. Vol. 22, no. 5, pp.963-968.
https://search.emarefa.net/detail/BIM-268122
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 968
Record ID
BIM-268122