Rare case of spot diagnosis of nephrotic syndrome in a Saudi male

Abstract EN

A 26-year-old Saudi male school teacher presented with clinical features of nephritic syndrome.

Physical examination revealed loss of subcutaneous fat over the face and upper arms (partial lip dystrophy) and druse in both eyes.

The serum level of complement C3 was low, with normal C4.

Renal biopsy revealed features consistent with membranoproliferative glomeruli- nephritis (MPGN) type II [Dense Deposit Disease (DDD)].

He was treated with prednisolone and mycophenolate moiety with partial remission.

He also received Lipitor and lisinopril.

The occurrence of partial lipo-dystrophy and druses in a patient with nephritic syndrome provides a rare clinical opportunity of making a bedside diagnosis of type II MPGN even before kidney biopsy.