End-stage renal disease in the el-minia governorate, upper Egypt : an epidemiological study

Abstract EN

We had earlier conducted two cross-sectional studies on the epidemiology of end stage renal disease (ESRD) in the El-Mania Governorate.

The aim of this study is to assess the prevalence, etiology and risk factors for ESRD in the El-Mania Governorate during the year 2006.

Patients on renal replacement therapy (RRT), numbering 1356, were recruited into this study.

A standardized questionnaire was completed including demographics, family history, and risk factors for ESRD, environmental exposure to toxins, work conditions, social history and causes of death.

Only 800 (59%) of the 1356 patients agreed to participate in this study.

Their mean age was 46 ± 13 years, median 43 (range 18-80).

The male vs.

female ratio was 65% vs.

35%.

The etiology of ESRD was unknown in 27%, hypertension in 20%, chronic glomerulonephritis in 11%, obstructive uropathy in 12%, bilhaziasis in 3%, analgesic nephropathy in 5%, chronic pyelonephritis in 5%, diabetic nephropathy in 8% and others, e.g.

lupus in 9%.

The overall prevalence of ESRD was 308 per million populations (pmp).

The modalities of RRT used on the study patients included hemodialysis (HD) in 1315 (97%), peritoneal dialysis (PD) in 27 (2%) and renal transplantation in 14 patients (1%).

The death rate was 190/1000.

Our study suggests that the epidemiology of ESRD in the El-Mania Governorate is different from that in European countries and the US and thus, region-specific interventions must be developed to control the epidemic of ESRD in the world.