A study of the concordance between endoscopic gastritis and histological gastritis in nonulcer dyspeptic patients with and without helicobacter pylori infection

Abstract EN

Background / Aim : dyspepsia significantly impairs quality of life and is a major burden on healthcare funding.

Helicobacter pylori (H.

pylori) infection is the main cause of active chronic gastritis and peptic car disease in both adults and children.

patients &Methods : A total of 90 consecutive patients with dyspepsia attending Tanta University Hospitals for diagnostic paper gastrointestinal endoscopy and found have nonnuclear dyspepsia were enrolled in this study.

Eight basic endoscopic and histological types of gastritis (superficial, hemorrhagic, erosive, veracious, atrophic, met aplastic, hyperplastic and special types) were defined.

Four or more biopsy specimens were obtained from the lesser and the greater curvatures of the ant rum and the corpus of each patient and the histological findings of gastritis and Helicobacter pylori infection were assessed.

The endoscopic and the histological diagnoses were then compared in a blinded fashion.

Results : the sensitivity of endoscopic diagnosis in comparison to histological diagnosis of superficial gastritis, hemorrhagic gastritis, erosive gastritis, veracious gastritis, atrophic gastritis, hyperplastic gastritis, and congestive gastropathy were 86 %, 100 %, 67 %, 50 %, 90 %, 25 %, and 50% respectively.

Conclusion : the following conclusions were drawn: (i) it is better to use six basic types : superficial, hemorrhagic, erosive, veracious, atrophic and special types; (ii) it is appropriate to exclude met aplastic and hyperplastic types from the fundamental types; however, they might be additionally described if they are significant ; (iii) The significant endoscopic features in the patients infected with H.

pylori were erythema, edema, exudate, friability, nodularity, vascular pattern, flat erosion, atrophy, and hypertrophy.