Role of high sensitivity c reactive protein and bone scintigraphy in the assessment of erosive osteoarthritis of the hand
Author
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 34, Issue 4 (31 Oct. 2007), pp.535-542, 8 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
2007-10-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
Objective : to investigate the role of serum C reactive protein (CRP) as a marker of erosive osteoarthritis (EOA) of the hand.
Methods : sixty patients, 40 with EOA and 20 with non-EOA of the hand, were included in the study and analyzed for radiographic score (RS), number of erosions, and joint count (JC) at clinical observation and at bone scintigraphy.
CRP was assayed in a serum sample by a highly sensitive immunonephelometric method.
Results : The median (interquartile range) CRP level was 4.7 (2.4–6.9) mg / l in the EOA and 2.1 (0.5–4.9) mg / l in the non-EOA group (p = 0.001).
In all patients, CRP correlated with RS (p<0.001), and mainly with JC at clinical observation (p < 0.001) and at bone scintigraphy (p < 0.001).
The correlation of CRP with RS and JC was confirmed at clinical observation and at bone scintigraphy in the EOA subgroup, but only with JC at clinical observation in the non-EOA subgroup.
Conclusions : CRP levels are higher in EOA than in non-EOA patients.
These levels probably reflect the disease activity of EOA, as suggested by correlations between CRP and JC at clinical observation and at bone scintigraphy.
American Psychological Association (APA)
Amin, Raji Tantawi. 2007. Role of high sensitivity c reactive protein and bone scintigraphy in the assessment of erosive osteoarthritis of the hand. Egyptian Rheumatology and Rehabilitation،Vol. 34, no. 4, pp.535-542.
https://search.emarefa.net/detail/BIM-27205
Modern Language Association (MLA)
Amin, Raji Tantawi. Role of high sensitivity c reactive protein and bone scintigraphy in the assessment of erosive osteoarthritis of the hand. Egyptian Rheumatology and Rehabilitation Vol. 34, no. 4 (Oct. 2007), pp.535-542.
https://search.emarefa.net/detail/BIM-27205
American Medical Association (AMA)
Amin, Raji Tantawi. Role of high sensitivity c reactive protein and bone scintigraphy in the assessment of erosive osteoarthritis of the hand. Egyptian Rheumatology and Rehabilitation. 2007. Vol. 34, no. 4, pp.535-542.
https://search.emarefa.net/detail/BIM-27205
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references: p. 541-542
Record ID
BIM-27205