Pleurodesic effect of bioglass in experimental rabbits
Joint Authors
Ergin, Muhammad
Ozyurt, H.
Bassorgun, C. I.
Yeginsu, A.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 11, Issue 3 (31 Jul. 2009), pp.254-258, 5 p.
Publisher
Publication Date
2009-07-31
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : pleurodesis has been a widely used treatment option for recurrent and persistent pleural effusions and air leaks.
However, an ideal pleurodesing agent has not been found yet.
The purpose of this study was to investigate the dose dependent effects of biogas’s on pleurodesis.
Methods : fifty six male, New Zealand rabbits weighing 3000-3500 gr were used in this study.
After right chest tube insertion, 35, 70, 150, and 400 mg / biogas’s; and 70 and 400 mg / kg talc in saline solution were administered through the chest tube into the pleural cavity.
One ml / kg isotonic saline solution was administered in the control group.
After 4 weeks, the rabbits were sacrificed for pleurodesis evaluation.
Results : biogas’s 400 and Talc 400 had a higher pleurodesic effect than the other doses with no statistically significant difference.
Local inflammation, fibrosis and particle dissemination were significantly higher in Biogas’s 400 and Talc 400 than in the controls.
Talc 400 caused more inflammation and more particle accumulation than those by biogas’s 400.
Conclusions : biogas’s may be a valuable pleurodesic agent.
However, further studies are needed for more definitive results.
American Psychological Association (APA)
Yeginsu, A.& Ergin, Muhammad& Ozyurt, H.& Bassorgun, C. I.. 2009. Pleurodesic effect of bioglass in experimental rabbits. Iranian Red Crescent Medical Journal،Vol. 11, no. 3, pp.254-258.
https://search.emarefa.net/detail/BIM-27282
Modern Language Association (MLA)
Yeginsu, A.…[et al.]. Pleurodesic effect of bioglass in experimental rabbits. Iranian Red Crescent Medical Journal Vol. 11, no. 3 (Jul. 2009), pp.254-258.
https://search.emarefa.net/detail/BIM-27282
American Medical Association (AMA)
Yeginsu, A.& Ergin, Muhammad& Ozyurt, H.& Bassorgun, C. I.. Pleurodesic effect of bioglass in experimental rabbits. Iranian Red Crescent Medical Journal. 2009. Vol. 11, no. 3, pp.254-258.
https://search.emarefa.net/detail/BIM-27282
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 247-258
Record ID
BIM-27282