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Esthesioneuroblastoma : the role of post-operative irradiation after complete surgical resection
Joint Authors
Abu Ziyadah, Muhammad Abd al-Hamid
Eisbruch, Avraham
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 22, Issue 2 (30 Jun. 2010), pp.143-148, 6 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2010-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Esthesioneuroblastoma is a rare tumor and this retrospective report was done to evaluate the role of post-operative radiotherapy after complete surgical resection of the tumor.
Patients and Methods : Twenty nine patients with Esthesioneuroblastoma of Kadish stages A (1), B (19), C (6) And unknown (3) were retrospectively identified through the hospital data-base, patients’ charts, imaging studies and computerized notes between 1995 to 2007 at Department of Radiation Oncology, University of Michigan, U.S.A.
Results : After complete surgical resection (mostly craniofacial resection) of the tumor, 13 (44.8 %) patients received post-operative radiotherapy to the tumor bed and 16 (45.2 %) patients did not receive.
Only one patient received adjuvant nodal irradiation.
At a median follow-up 80 months, local recurrence developed in 11 of 16 (68.7 %) patients in the group which did not receive postoperative radiotherapy, compared with 2 of 13 (15.3 %) patients in the group which received.
Disease free cumulative survival rate at 5-years was 88 % for the group which received post-operative radiotherapy compared with 35 % for the group which did not receive (p = 0.02).
Lymph node recurrence in retropharyngeal and level II nodes was observed in 7 (24 %) patients of whole group.
Conclusion : Adjuvant radiotherapy to the tumor bed after craniofacial resection improves significantly local control and disease free survival.
Our results suggest that in addition to the tumor bed, prophylactic irradiation of the upper neck is necessary in patients with Kadish stages B and C.
American Psychological Association (APA)
Abu Ziyadah, Muhammad Abd al-Hamid& Eisbruch, Avraham. 2010. Esthesioneuroblastoma : the role of post-operative irradiation after complete surgical resection. Journal of the Egyptian National Cancer Institute،Vol. 22, no. 2, pp.143-148.
https://search.emarefa.net/detail/BIM-273813
Modern Language Association (MLA)
Abu Ziyadah, Muhammad Abd al-Hamid& Eisbruch, Avraham. Esthesioneuroblastoma : the role of post-operative irradiation after complete surgical resection. Journal of the Egyptian National Cancer Institute Vol. 22, no. 2 (Jun. 2010), pp.143-148.
https://search.emarefa.net/detail/BIM-273813
American Medical Association (AMA)
Abu Ziyadah, Muhammad Abd al-Hamid& Eisbruch, Avraham. Esthesioneuroblastoma : the role of post-operative irradiation after complete surgical resection. Journal of the Egyptian National Cancer Institute. 2010. Vol. 22, no. 2, pp.143-148.
https://search.emarefa.net/detail/BIM-273813
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 148
Record ID
BIM-273813