Radical retropubic prostatectomy : a review of 8 years of experience

Abstract EN

Objectives : different modalities for treating prostate cancer are evolving worldwide.

Radical prostatectomy is still ranking on top of the list for organ- confined disease.

This study was conducted out to describe the indications, surgical technique, complications and outcome of radical retro pubic prostatectomy for prostate cancer over an 8-year period at Prince Hussein Center of Urology and Organ Transplant, King Hussein Medical Center.

Methods : between August 1999 and June 2007, a total of 81 patients (age range 50-68 years) underwent radical retro pubic prostatectomy for organ confined prostate cancer (stage T1a-T2c) based on Prostate Specific Antigen values, histopathology reports (Gleason Score 4-7) and negative metastatic work up.

Follow-up of these patients ranged between 1 and 7 years.

The medical records of these patients were reviewed, and analyzed regarding indications, surgical technique, complications, and outcome.

Results : none of the patients had pelvic lymph node involvement, and surgery accomplished in 2.5-3.5 hours.

Estimated blood loss was between 500 and 2000ml.

Early continence, within 4 weeks after surgery, was achieved in 51 / 81 (62.9 %) and in 98.7 % after one year.

Potency within 1 year was achieved in 42 patients (51.8 %), but with medications this number reached 52 (64 %).

Margin positive histopathology reports were seen in 12 patients (14.8 %) warranting further treatment with either radiotherapy or hormonal therapy.

Mortality rate in the study group was 2.5 % as a result of disease progression and dissemination.

Conclusions : radical retro pubic Prostatectomy stands the gold standard method of treatment for localized prostate cancer with excellent results in cure and tumor control.