A comparative diametric study of adjuvant 3D conformal radiotherapy for operable stomach cancer versus AP-PA conventional radiotherapy in NCI-Cairo

Abstract EN

Purpose : this study was to compare this multiple field conformal technique to the AP-PA technique with respect to target volume coverage and dose to normal Tissues.

Materials and Methods: Seventeen patients with stages II-III adenocarcinoma of the stomach were treated with adjuvant postoperative chemo radiotherapy presented to radiotherapy department in National Cancer Institute, Cairo in period between February 2009 to March 2010 using 3D conformal radiotherapy technique that consisted of a monoisocentric arrangement employing 4-6 radiation fields.

For each patient, a second radiotherapy treatment plan was done using an antroposterior (AP-PA) fields, the two techniques were then compared using dose volume histogram (DVH) analysis Results : comparing different DVHs, it was found that the planning target volume (PTV) was adequately covered in both (3D & 2D) plans while the left kidney and spinal cord demonstrate lower radiation doses on using the conformal technique.

The liver doses is higher in the 3D tecq, but still well below liver tolerance.

Conclusions : both 3D conformal radiotherapy and AP-PA conventional techniques doses are within range of normal tissues tolerance.

Regarding the left kidney and spinal cord the 3D conformal radiotherapy is superior than the AP-PA conventional techniques but with higher doses to the liver in the 3D conformal radiotherapy compared to the AP-PA conventional techniques.