Identification and estimation of leucine aminopeptidase activity in the serum and ascitic fluid of patients with schistosomiasis
Other Title(s)
تقدير النشاط الإنزيمي و التحليل الكهربي لإنزيم الليوسين أمينوببتيداز في المصل و سائل الاستسقاء في المرضى المصابين بالبلهارسيا هيماتوبيام
Joint Authors
Hammad, Wafa Ahmad
al-Aqqad, Majdi Abbas
Salim, Tahiyah Hashim
Hajju, Huwayda Abd al-Hakim Nafadi
Source
Issue
Vol. 35, Issue 2 (31 May. 2011), pp.183-192, 10 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2011-05-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Topics
Abstract EN
The activity and electrophoretic mobility or leucine aminopeptidase [LAP] were assessed in the sera of 100 patients with different clinical stages of Schistosoma hacmatobium infestation as well as in 20 sample of ascctic fluids obtained from patients with bilharzial hepatosplenomegaly associated with ascites matched with 20 healthy adult males sample as control.
Generally LAP activity was significantly higher in all patients.
The activity of serum LAP showed a progressive rise with the advance in the clinical condition.
The highest level was encountered in the sera of patients with bladder carcinoma and liver metastasis, leucine aminopeptidase was considerably found in the ascetic fluid.
The ratio of the activity or LAP in the ascetic fluid to its activity in the serum of the same patients was 14.5 where the enzyme diffuses from the blood to the ascetic fluid.
The enzyme detected by electrophoresis, in serum or ascetic fluid LAP migrated as a single component in the alpha1 -globulin faction.
The results are discussed and compared with those in the literature
American Psychological Association (APA)
Hammad, Wafa Ahmad& Salim, Tahiyah Hashim& Hajju, Huwayda Abd al-Hakim Nafadi& al-Aqqad, Majdi Abbas. 2011. Identification and estimation of leucine aminopeptidase activity in the serum and ascitic fluid of patients with schistosomiasis. Assiut Medical Journal،Vol. 35, no. 2, pp.183-192.
https://search.emarefa.net/detail/BIM-274346
Modern Language Association (MLA)
al-Aqqad, Majdi Abbas…[et al.]. Identification and estimation of leucine aminopeptidase activity in the serum and ascitic fluid of patients with schistosomiasis. Assiut Medical Journal Vol. 35, no. 2 (May. 2011), pp.183-192.
https://search.emarefa.net/detail/BIM-274346
American Medical Association (AMA)
Hammad, Wafa Ahmad& Salim, Tahiyah Hashim& Hajju, Huwayda Abd al-Hakim Nafadi& al-Aqqad, Majdi Abbas. Identification and estimation of leucine aminopeptidase activity in the serum and ascitic fluid of patients with schistosomiasis. Assiut Medical Journal. 2011. Vol. 35, no. 2, pp.183-192.
https://search.emarefa.net/detail/BIM-274346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 190-192
Record ID
BIM-274346