Prevalence of multidrug resistant enterococci in nosocomial infection in Gaza strip

Abstract EN

Enterococci leading causes of nosocomial infection like bacteremia, surgical wound infection, lower respiratory tract, and urinary tract infection, these organisms are becoming resistant to many and sometimes all standard antibiotics, most enterococci infections are caused by Enterococcus facials which are more likely to express traits related to over virulence.

The remaining infections are mostly caused by Enterococcus fascism, a species virtually devoid of known overt pathogenic traits but more likely to be resistant to even antibiotics.

309 clinical samples included (116 Urine, 104 Pus, 67 Blood, and 22 Sputum) samples were processed to find the prevalence rate of enterococci and identify the species of clinical isolates of enterococci.

Screening of various clinical specimens revealed that enterococci were prevalent in 1.9 % of the total nosocomial infected cases.

The most effective antibiotics were Linzolid followed by Nitrofurantoin, Chloramphenicol and Ciprofloxacin.

Where Amikacin, Gentamicin, Erythromycin and Lincomycin showed moderate activities.

At the same time Methicillin, Ampicillin, Tetracycline, Aztreonam, Cefuroxime and Cefotaxim showed resistance.

None of the available Cephalosporins, Monobactams, Aztreonam or semisynthetic Penicillins (Naficillin, Oxacillin) have any activity against enterococci.

Vancomycin resistant strains were recorded in this study the distribution of enterococci cases showed highest rate in lower respiratory tract infection (4.5 %), blood stream infection (3 %), surgical wound infection (1.9 %), and urinary tract infection (80.0 %).