Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients
Joint Authors
Ali, Asik Ali Muhammad
Sundararaj, Saravanan
Ibrahim, Georgi
Lesley, Nansi
Sundaram, Varun
Mathew, Milly
Fathima, Nusrath
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 20, Issue 6 (31 Dec. 2009), pp.984-990, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2009-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
Limited data exist regarding long-term allograft survival in South Asian patients in the era of modern immunosuppressive therapy.
This retrospective cohort study was undertaken to see the graft survival based on serial eGFR, immunosuppressive therapy, BMI and other confounding factors including smoking in patients who have undergone renal transplantation in a tertiary care center in south India.
Three hundred and three kidney transplant recipients including live and cadaveric transplantation performed between 2001 and 2006 were included in this study.
The mean graft survival after transplantation was 6.38 ± 0.11 years, graft survival at one, two, three and five years were 95.7 %, 92.72 %, 91.72 % and 89.21 %, respectively.
The mean serum cretonne and eGFR in the biopsy proven acute rejection (BPAR) group were 1.74 ± 0.94 mg / dL and 43.73 ± 13.65 mL / min compared with 1.24 ± 0.59 mg / dL and 61.50 ± 17.40 mL / min in the non-BPAR group (P < 0.001 and P = 0.0159) respectively.
The mean BMI in the BPAR group at one year was 26.59 ± 3.18 kg/m 2 compared with 21.63 ± 2.29 kg/m 2 in the non-BPAR group (P < 0.05).
The mean graft survival in patients who were smokers at the time of pretransplant evaluation was 89.3 % compared with 92.5 % in the non-smokers (P = 0.347).
This retrospective cohort study found that serial eGFR, body mass index and smoking were significant predictors of graft survival following renal transplantation in South Asian patients.
American Psychological Association (APA)
Ali, Asik Ali Muhammad& Ibrahim, Georgi& Mathew, Milly& Fathima, Nusrath& Sundararaj, Saravanan& Sundaram, Varun…[et al.]. 2009. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 6, pp.984-990.
https://search.emarefa.net/detail/BIM-279671
Modern Language Association (MLA)
Ali, Asik Ali Muhammad…[et al.]. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 6 (Dec. 2009), pp.984-990.
https://search.emarefa.net/detail/BIM-279671
American Medical Association (AMA)
Ali, Asik Ali Muhammad& Ibrahim, Georgi& Mathew, Milly& Fathima, Nusrath& Sundararaj, Saravanan& Sundaram, Varun…[et al.]. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 6, pp.984-990.
https://search.emarefa.net/detail/BIM-279671
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 988-990
Record ID
BIM-279671