Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients

Joint Authors

Ali, Asik Ali Muhammad
Sundararaj, Saravanan
Ibrahim, Georgi
Lesley, Nansi
Sundaram, Varun
Mathew, Milly
Fathima, Nusrath

Source

Saudi Journal of Kidney Diseases and Transplantation

Issue

Vol. 20, Issue 6 (31 Dec. 2009), pp.984-990, 7 p.

Publisher

Saudi Center for Organ Transplantation

Publication Date

2009-12-31

Country of Publication

Saudi Arabia

No. of Pages

7

Main Subjects

Medicine

Topics

Abstract EN

Limited data exist regarding long-term allograft survival in South Asian patients in the era of modern immunosuppressive therapy.

This retrospective cohort study was undertaken to see the graft survival based on serial eGFR, immunosuppressive therapy, BMI and other confounding factors including smoking in patients who have undergone renal transplantation in a tertiary care center in south India.

Three hundred and three kidney transplant recipients including live and cadaveric transplantation performed between 2001 and 2006 were included in this study.

The mean graft survival after transplantation was 6.38 ± 0.11 years, graft survival at one, two, three and five years were 95.7 %, 92.72 %, 91.72 % and 89.21 %, respectively.

The mean serum cretonne and eGFR in the biopsy proven acute rejection (BPAR) group were 1.74 ± 0.94 mg / dL and 43.73 ± 13.65 mL / min compared with 1.24 ± 0.59 mg / dL and 61.50 ± 17.40 mL / min in the non-BPAR group (P < 0.001 and P = 0.0159) respectively.

The mean BMI in the BPAR group at one year was 26.59 ± 3.18 kg/m 2 compared with 21.63 ± 2.29 kg/m 2 in the non-BPAR group (P < 0.05).

The mean graft survival in patients who were smokers at the time of pretransplant evaluation was 89.3 % compared with 92.5 % in the non-smokers (P = 0.347).

This retrospective cohort study found that serial eGFR, body mass index and smoking were significant predictors of graft survival following renal transplantation in South Asian patients.

American Psychological Association (APA)

Ali, Asik Ali Muhammad& Ibrahim, Georgi& Mathew, Milly& Fathima, Nusrath& Sundararaj, Saravanan& Sundaram, Varun…[et al.]. 2009. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 6, pp.984-990.
https://search.emarefa.net/detail/BIM-279671

Modern Language Association (MLA)

Ali, Asik Ali Muhammad…[et al.]. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 6 (Dec. 2009), pp.984-990.
https://search.emarefa.net/detail/BIM-279671

American Medical Association (AMA)

Ali, Asik Ali Muhammad& Ibrahim, Georgi& Mathew, Milly& Fathima, Nusrath& Sundararaj, Saravanan& Sundaram, Varun…[et al.]. Can serial eGFR, body mass index and smoking predict renal allograft survival in south Asian patients. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 6, pp.984-990.
https://search.emarefa.net/detail/BIM-279671

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 988-990

Record ID

BIM-279671